Dealing with PMS

Dealing with PMS

12:57 09 August in News

Premenstrual syndrome is the name for a collection of physical and emotional symptoms that many women experience in the days or weeks leading up to their menses. While hormone imbalances are an obvious contributing component to these symptoms, new evidence points to neurotransmitters – chemical messengers – as another significant factor.


What the current research says about PMS…

In the June 2012 edition of Menopause International, UCLA researchers reported their findings on the pathophysiology of PMS and premenstrual dysphoric disorder as it relates to neurotransmitters. Clinically it has been well documented that premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PDD) – a more severe form of PMS – are triggered by hormonal events ensuing after ovulation.  PMS and PDD symptoms can begin midcycle and are related to the production of progesterone by the ovary. The two best-studied and relevant neurotransmitter systems implicated in the PMS symptoms are the GABAergic and the serotonergic systems.


GABA helps make us calm…

GABA is a calming neurotransmitter while serotonin makes us feel happy.  Metabolites of progesterone formed by the corpus luteum of the ovary and in the brain decrease the calming activity of GABA in the brain leading to symptoms such as anxiety, irritability and insomnia. Additionally, the lowering of serotonin can give rise to PMS-like symptoms.


What you can do about it…

A naturopathic approach to PMS will employ natural remedies such as herbs and nutraceuticals to help rebalance not only the body’s hormones but also the chemical messengers in the brain associated with PMS symptoms. Schedule an appointment with Dr. Suzanna Ivanovics, ND – Naturopathic doctor.  Appointments can be scheduled by phoning our clinic at 416.972.9355.  Inquiries are welcome by emailing Dr. Ivanovics at

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